Evolve Health now offers an innovative solution—Spravato treatment, a groundbreaking therapy that has transformed the lives of many who thought their condition was beyond help.
Imagine reclaiming the joy and vibrancy you thought you had lost, through a treatment method that is both safe and scientifically backed. Evolve Health’s dedicated professionals are here to guide you every step of the way, ensuring a comfortable and supportive environment.
Don’t wait to turn a new page in your life. Contact Evolve Health today to schedule your consultation and learn more about how Spravato treatment can help you.
Spravato, scientifically known as esketamine, is a derivative of ketamine, a medication long used for anesthesia and pain relief. Unlike ketamine, which is a racemic mixture of two mirror-image molecules, Spravato contains only the “S” enantiomer of ketamine, which is believed to have greater antidepressant effects. This distinction makes Spravato a particularly potent option for treating severe depression.
Esketamine operates uniquely compared to traditional antidepressants like selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs). It targets the N-methyl-D-aspartate (NMDA) receptors in the brain, which are involved in mood regulation and cognitive functions. By modulating these receptors, Spravato can help to restore synaptic connections in brain areas affected by depression. This action can lead to rapid improvements in mood, often within hours or days, whereas traditional antidepressants may take weeks to become effective.
The U.S. Food and Drug Administration (FDA) approved Spravato in 2019 for use in adults with treatment-resistant depression, which is defined as depression that has not responded adequately to at least two different antidepressant treatments during the current episode. It is also approved for depressive symptoms in adults with major depressive disorder (MDD) with acute suicidal ideation or behavior. Spravato is administered under medical supervision, typically in a clinic or hospital setting, where healthcare professionals can monitor the patient for any side effects and ensure the safety and efficacy of the treatment.
The approval of Spravato marked a significant milestone in the field of psychiatry, providing a new tool for doctors to combat one of the many disabling conditions worldwide. Its ability to act quickly is especially critical for patients experiencing severe symptoms of depression, who need immediate relief to prevent further deterioration of their mental health.
Evolve Health, recognizing the profound potential of this treatment, incorporates Spravato into their mental health services, offering it to patients who meet the clinical criteria for its use. Their approach ensures that each patient’s treatment plan is tailored to their specific needs, maximizing the likelihood of a positive outcome.
Most insurance companies now cover Spravato therapy; with a referral, our insurance coordinator can assist with your preauthorization. FDA guidelines state twice a week for four weeks and then weekly for weeks 5-8, and then move to once every one week or two-week dosing. The Spravato website has a nice graphic idea that might help patients who are visual learners.
IV Ketamine
Intravenous infusion is administered over a predetermined amount of time to allow the patient to transition into a relaxed state.
Spravato (Nasal Spray):
The nasal spray consists of two to three intranasal administrations done in five-minute increments.
IV Ketamine
Determined by weight and titrated to the effectiveness and comfort of the patient.
Spravato (Nasal Spray):
Two dose options, 56mg and 84mg. The appropriate dose will be selected by the healthcare provider.
IV Ketamine
Six infusions over the course of two to three weeks, followed by maintenance infusions as needed. Appointments last about 90 minutes.
Spravato (Nasal Spray):
Two doses per week for the first four weeks, followed by one dose per week for the next four weeks, then one dose every one to two weeks as recommended by your provider.
IV Ketamine
IV infusions have a 100% bioavailability (absorption).
Spravato (Nasal Spray):
Nasal spray has a wide variability of absorption, generally between 40-50%. Stuffy nose or swallowing can affect the amount of medication that reaches the bloodstream.
IV Ketamine
Must be diagnosed with depression, anxiety, suicidal ideation, PTSD, OCD, eating disorders, or end-of-life care.
Spravato (Nasal Spray):
Must be diagnosed with depression and have not responded sufficiently to two or more oral antidepressants.
IV Ketamine
Currently, ketamine is not covered by insurance.
Spravato (Nasal Spray):
Esketamine is covered by most insurance.
IV Ketamine
People may experience dissociation, nausea, anxiety, sweating, increased blood pressure, or sedation, and typically resolve before the end of the treatment.
Spravato (Nasal Spray):
Common side effects include dissociation, dizziness, nausea, fatigue, or increased blood pressure, and typically resolve before the end of the treatment.
The journey for patients choosing Spravato treatment at Evolve Health is carefully designed to provide maximum efficacy and comfort throughout the process. Here’s what a typical treatment pathway looks like:
The process begins with a thorough evaluation by a qualified mental health professional at Evolve Health. This session aims to understand the patient’s medical history, current health status, and prior treatment responses. It’s crucial to determine whether Spravato is a suitable option based on the patient’s specific needs and conditions.
Once a patient is deemed suitable for Spravato, they start a series of treatment sessions. These are conducted in a quiet, private space within Evolve Health’s facilities, designed to promote a calm and supportive environment. During each session, Spravato is administered as a nasal spray under close supervision. Patients are monitored for any immediate reactions, with medical staff available to provide support and manage any adverse effects.
After each treatment session, patients remain under observation for symptoms of sedation or dissociation, which are possible side effects of Spravato. The follow-up process also includes regular check-ins to assess the treatment’s effectiveness and any adjustments needed to the treatment plan. This ongoing monitoring is crucial to achieving the best possible outcome for the patient.
Spravato treatment at Evolve Health represents a beacon of hope for many who have struggled with treatment-resistant depression. Through a combination of advanced medical treatments, comprehensive support, and expert care, Evolve Health provides its patients with a new path to managing their mental health. The clinic’s dedication to patient-centered care ensures that each individual’s journey through depression treatment is as smooth and effective as possible.
If you or someone you know is battling depression and has not found relief with traditional medications, consider reaching out to Evolve Health in Portland, OR. Our team is ready to answer any questions you have about Spravato treatment and can help you determine if it’s the right option for you. Don’t wait to take the next step towards a healthier, happier life. Contact Evolve Health today to schedule your consultation and learn more about how Spravato Treatment can help you on your path to recovery.
Evolve Health is an outpatient mental health clinic specializing in treating patients with major depressive disorder and treatment-resistant depression with Spravato (esketamine) nasal spray, and ketamine infusions. We are a team of medical providers who are excited to offer a refreshing, innovative approach to medicine. We work collaboratively with your existing treatment team. Our philosophy redefines the healing experience with cutting-edge science and wellness practices.
16100 NW Cornell Rd, Suite 190
Phone (971) 405-5960
Fax (971) 405-5961
BUSINESS HOURS:
Monday-Thursday -> 9am-8:30pm
Friday-Sunday -> closed
2255 NW Shevlin Park Rd, Suite 110
Bend, OR 97703
Phone (541) 728-2525
Fax (503) 917-4971
BUSINESS HOURS:
Monday-Thursday -> 9am-8pm
Friday-Sunday -> closed
6400 SE Lake Rd, Suite 155
Portland, OR 97222
Phone (503) 447-3285
Fax (503) 917-4971
BUSINESS HOURS:
Monday-Friday -> 9am-8:30pm
Saturday-Sunday -> closed
